Cell cultures are routinely used in a number of laboratories and are one of the main research tools in the biomedical sciences. Culture media enabling the proliferation of eukaryotic cells have a very complex composition. For the cultivation of most cells, it is necessary to&#...

In this paper, we evaluated the number of infections and mortality rates of the COVID-19 epidemic in the Pilsen region using publicly available sources. In the Pilsen region, the number of deaths varied by district, from 0.9% (Pilsen-City and Pilsen-North) to 1.5% in the Tacho...

The bachelor thesis focuses on a topic that has become increasingly actual in recent years, which is malignant melanoma. MicroRNA molecules that could find application as new biomarkers bring favourable perspectives to the issue of early detection of this disease, choice of approp...

The bachelor's thesis deals with laboratory diagnostics and the occurrence of dermatophytes in the University Hospital Pilsen. The work is divided into theoretical and practical part. The theoretical part describes fungi in general, their reproduction and classification, diseases and subsequently&...

Antibiotics have been discovered to treat bacterial infections. To this day, their invention is considered like a great success of medicine. But their side effects are beginning to manifest themselves significantly in antibiotic resistance. The development of antibiotic resistance is increasing&#...

This bachelor thesis is focused on detecting and validating bonds of different types of mo-noclonal antibodies, mainly on the anti-PCNA antibody. The validation process of these antibodies has been done using several methods, wich can show or quantify the bond of the antibody-antigen&#x...

The bachelor thesis deals with issue of vaccination and immunization in the Czech Re-public. The work is divided into theoretical and practical part. The theoretical part is fo-cused on the history of vaccination, explains basic concepts such as immunity, immuni-zation. It also shows&#x...

In recent years, the occurrence of C. difficile has increased. Infections caused by this clostridium are perceived as nosocomial infections, because they are related to anti-biotic treatment. This bachelor thesis does not deal only with C. difficile but also with other members of t...

This bachelor thesis consists of comparing two methods. The referential method was flow cytometry, and it was compared with a new, experimental method: Pheno-Immuno Computing (PIC). The theoretical part of this thesis is focused on T-cells, their development, populations and their role ...

This bachelor thesis will be about the comparison of CD 69 expression determination using the newly developed Pheno-Immuno Computing method and flow cytometry in activated T lymphocytes. For the determination will be used heparinized whole blood samples provided by volunteers. The theoretica...

This bachelor's thesis deals with traumatic spine injuries and diagnostic methods used in their imaging. The thesis consists of a theoretical part and a practical part. The theoretical part is focused on anatomical description of spine, traumatic injuries, diagnostic methods, algorithms ...

The bachelor thesis is focused on radiological standards and clinical audits. The main goal is to describe the creation of local radiological standards and clinical audits. The theoretical part of the thesis describes local rediological standards and their compliance with national radiologic...

This bachelors thesis deal with problematics of the back pain treatment with help of nonvascular radiodiagnostic intervention techniques. The theoretical part describes basic anatomical structures which are contained in the area of our back and reasons why backpain can be caused. I am&#...

The bachelor's thesis is elaborated on the topic "Traumatology of the wrist and options of it's projection". The work consists of two parts - theoretical and practical. The first consists of the theory of anatomical structures of the upper limb and specifi...

This bachelor thesis deals with the possibilities of brain examination using computed tomography, indications for this examination and its use in practice. The theoretical part describes the principle and origin of X-rays in the introduction to the whole issue. Then these findings are&#...

This bachelor thesis is focused on the characterization of mucus substances in the chorionic villi of the placenta. 9 paraffin blocks of placenta with chorionic villi disease were selected from the archival material of the Šikl's Institute of Pathology in Pilsen. The tenth para...

The aim of the study was to compare creatinine clearance in 6hour and 24hour urine collaction of a selected group of patients and to determine whether the shortened urine coll-ection time affects the final value of creatinine clearance. For our study we selected a group o...

The bachelor thesis deals with late complications after radiotherapy. It is divided into two parts: theoretical and practical. The theoretical part briefly describes cancer, radiotherapy and the associated ionizing radiation. The most comprehensive charter of the theoretical part deals with compl...

The bachelor thesis titled "Biological therapy of colorectal cancer" is divided into the theoretical and practical part. The theoretical part describes anatomy, epidemiology, risk factors, symptoms, diagnostics, prevention and therapy. The practical part contains case studies of patients who ...

This bachelor's thesis deals with the possibilities of breast cancer diagnosis. The theoretical part is devoted to the theory, which deals mainly with available examination methods and their use for breast cancer. The practical part contains both quantitative and qualitative research. Th...