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dc.contributor.authorDodda, Jagan Mohan
dc.contributor.authorGhafouri Azar, Mina
dc.contributor.authorSadiku, Rotimi
dc.date.accessioned2022-01-31T11:00:31Z-
dc.date.available2022-01-31T11:00:31Z-
dc.date.issued2021
dc.identifier.citationDODDA, JM. GHAFOURI AZAR, M. SADIKU, R. Crosslinking Trends in Multicomponent Hydrogels for Biomedical Applications. MACROMOLECULAR BIOSCIENCE, 2021, roč. 21, č. 12, s. nestránkováno. ISSN: 1616-5187cs
dc.identifier.issn1616-5187
dc.identifier.uri2-s2.0-85117214723
dc.identifier.urihttp://hdl.handle.net/11025/46695
dc.format20 s.cs
dc.format.mimetypeapplication/pdf
dc.language.isoenen
dc.publisherJohn Wiley and Sons Incen
dc.relation.ispartofseriesMacromolecular Bioscienceen
dc.rights© Wiley-VCH GmbHen
dc.titleCrosslinking Trends in Multicomponent Hydrogels for Biomedical Applicationsen
dc.typečlánekcs
dc.typearticleen
dc.rights.accessopenAccessen
dc.type.versionpublishedVersionen
dc.description.abstract-translatedMulticomponent-based hydrogels are well established candidates for biomedical applications. However, certain aspects of multicomponent systems, e.g., crosslinking, structural binding, network formation, proteins/drug incorporation, etc., are challenging aspects to modern biomedical research. The types of crosslinking and network formation are crucial for the effective combination of multiple component systems. The creation of a complex system in the overall structure and the crosslinking efficiency of different polymeric chains in an organized fashion are crucially important, especially when the materials are for biomedical applications. Therefore, the engineering of hydrogel has to be, succinctly understood, carefully formulated, and expertly designed. The different crosslinking methods in use, hydrogen bonding, electrostatic interaction, coordination bonding, and self-assembly. The formations of double, triple, and multiple networks, are well established. A systematic study of the crosslinking mechanisms in multicomponent systems, in terms of the crosslinking types, network formation, intramolecular bonds between different structural units, and their potentials for biomedical applications, is lacking and therefore, these aspects require investigations. To this end, the present review, focuses on the recent advances in areas of the physical, chemical, and enzymatic crosslinking methods that are often, employed for the designing of multicomponent hydrogels.en
dc.subject.translatedcrosslinkingen
dc.subject.translatedhydrogelsen
dc.subject.translatedhydrogen bondingen
dc.subject.translatedmulticomponenten
dc.subject.translatednetwork formationen
dc.subject.translatedself-assemblyen
dc.identifier.doi10.1002/mabi.202100232
dc.type.statusPeer-revieweden
dc.identifier.document-number708768700001
dc.identifier.obd43934531
dc.project.IDEF17_048/0007280/Aplikace moderních technologií v medicíně a průmyslucs
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