Title:	Crosslinking Trends in Multicomponent Hydrogels for Biomedical Applications
Authors:	Dodda, Jagan Mohan Ghafouri Azar, Mina Sadiku, Rotimi
Citation:	DODDA, JM. GHAFOURI AZAR, M. SADIKU, R. Crosslinking Trends in Multicomponent Hydrogels for Biomedical Applications. MACROMOLECULAR BIOSCIENCE, 2021, roč. 21, č. 12, s. nestránkováno. ISSN: 1616-5187
Issue Date:	2021
Publisher:	John Wiley and Sons Inc
Document type:	článek article
URI:	2-s2.0-85117214723 http://hdl.handle.net/11025/46695
ISSN:	1616-5187
Keywords in different language:	crosslinking;hydrogels;hydrogen bonding;multicomponent;network formation;self-assembly
Abstract in different language:	Multicomponent-based hydrogels are well established candidates for biomedical applications. However, certain aspects of multicomponent systems, e.g., crosslinking, structural binding, network formation, proteins/drug incorporation, etc., are challenging aspects to modern biomedical research. The types of crosslinking and network formation are crucial for the effective combination of multiple component systems. The creation of a complex system in the overall structure and the crosslinking efficiency of different polymeric chains in an organized fashion are crucially important, especially when the materials are for biomedical applications. Therefore, the engineering of hydrogel has to be, succinctly understood, carefully formulated, and expertly designed. The different crosslinking methods in use, hydrogen bonding, electrostatic interaction, coordination bonding, and self-assembly. The formations of double, triple, and multiple networks, are well established. A systematic study of the crosslinking mechanisms in multicomponent systems, in terms of the crosslinking types, network formation, intramolecular bonds between different structural units, and their potentials for biomedical applications, is lacking and therefore, these aspects require investigations. To this end, the present review, focuses on the recent advances in areas of the physical, chemical, and enzymatic crosslinking methods that are often, employed for the designing of multicomponent hydrogels.
Rights:	© Wiley-VCH GmbH
Appears in Collections:	Články / Articles OBD

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.