Title:	Multiscale modelling of liver perfusion
Authors:	Rohan, Eduard Turjanicová, Jana Lukeš, Vladimír
Citation:	ROHAN, E., TURJANICOVÁ, J., LUKEŠ, V. Multiscale modelling of liver perfusion. In: 15th International Conference on Computational Plasticity. Fundamentals and Applications, COMPLAS 2019. Barcelona: International Center for Numerical Methods in Engineering, 2019. s. 343-353. ISBN 978-84-949194-7-3.
Issue Date:	2019
Publisher:	International Center for Numerical Methods in Engineering
Document type:	konferenční příspěvek conferenceObject
URI:	2-s2.0-85101984839 http://hdl.handle.net/11025/43632
ISBN:	978-84-949194-7-3
Keywords in different language:	Homogenization;Double Porosity;Liver Tissue;Perfusion;Darcy-Brinkman model
Abstract in different language:	We compare two homogenized models of the microcirculation which rely on different assumptions. The first model has been derived by the homogenization of the mesoscopic structure with the double-porosity medium represented by the Biot model with large contrasts in the permeability coefficients constituting the Darcy law. The newly developed so-called Biot-Darcy-Brinkman (BDB) model is described in the paper; it arises from a two-stage homogenization of the fluid-structure interaction problem which requires geometric representations of the sinusoidal and the inter-lobular vasculatures associated with venous compartments, the portal and the hepatic veins. An illustrative example shows a good correspondence between the two models.
Rights:	Plný text je přístupný v rámci univerzity přihlášeným uživatelům. © International Center for Numerical Methods in Engineering
Appears in Collections:	Konferenční příspěvky / Conference papers (NTIS) Konferenční příspěvky / Conference Papers (KME) OBD

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